George Wilcoxon participated in football and basketball at Mount Union from 1925-1928. He earned two varsity letters in both football and basketball. In football he played running back and quarterback. In basketball, Wilcoxon earned All-Ohio honors both years. He played the position of forward and helped win two conference titles for Mount Union. Wilcoxon played professional basketball for the Canton Orphans, Salem Althouse, and Alliance Studebakers until 1967.